Literature summary for 2.8.2.15 extracted from

Huang, Y.H.; Lee, C.Y.; Tai, P.J.; Yen, C.C.; Liao, C.Y.; Chen, W.J.; Liao, C.J.; Cheng, W.L.; Chen, R.N.; Wu, S.M.; Wang, C.S.; Lin, K.H.
Indirect regulation of human dehydroepiandrosterone sulfotransferase family 1A member 2 by thyroid hormones (2006), Endocrinology, 147, 2481-2489.

Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	SULT2A1 is a target gene for metabolic regulation/induction by thyroid hormone T3, T3 overexpressing cell s show increased SULT2A1 expression, indirect regulation mechanism via the transcription factor steroidogenic factor 1, SF1, overview	Homo sapiens

Cloned(Commentary)

Cloned (Comment)	Organism
SULT2A1 is a target gene for metabolic regulation/induction by thyroid hormone T3, T3 overexpressing Hep-G2 cells, with co-expression of the T3-receptor-alpha, show increased SULT2A1 expression in a DNA microarray analysis, 5fold at protein level and 9fold at mRNA level, which is inhibited by cycloheximide indicating an indirect regulation mechanism via the transcription factor steroidogenic factor 1, SF1, SULT2A1 contains seven SF1 binding sites, analysis of promoter activity in wild-type and truncation mutants of the enzyme, overview	Homo sapiens

Cloned (Comment)

Organism

SULT2A1 is a target gene for metabolic regulation/induction by thyroid hormone T3, T3 overexpressing Hep-G2 cells, with co-expression of the T3-receptor-alpha, show increased SULT2A1 expression in a DNA microarray analysis, 5fold at protein level and 9fold at mRNA level, which is inhibited by cycloheximide indicating an indirect regulation mechanism via the transcription factor steroidogenic factor 1, SF1, SULT2A1 contains seven SF1 binding sites, analysis of promoter activity in wild-type and truncation mutants of the enzyme, overview

Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
additional information	construction of truncation mutants of SULT2A1 for analysis of SF1 binding sites and promoter activity, overview	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
nucleus	-	Homo sapiens	5634	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
Hep-G2 cell	-	Homo sapiens	-
liver	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
dehydroepiandrosterone sulfotransferase family 1A member 2	-	Homo sapiens
SULT2A1	-	Homo sapiens